Question

In May 2023, the FDA approved the first two vaccines against this virus, one made by Pfizer and one by GSK. For 10 points each:
[10h] The feared “tripledemic” of winter respiratory infections is caused by influenza, SARS-CoV-2, and what third virus, the most common cause of infant hospitalization in the US?
ANSWER: RSV [or respiratory syncytial virus; accept RSV A or RSV B]
[10e] To protect fetuses against RSV, Pfizer’s vaccine was approved for use by mothers who are in the last of these 13-week-long stages of pregnancy.
ANSWER: trimesters [or third trimester]
[10m] Both vaccines contain a form of RSV’s F protein that has undergone this post-translational modification. The endoplasmic reticulum performs this process by attaching mannose or GlcNAc (“glick-nack”) to proteins.
ANSWER: glycosylation [or N-linked glycosylation or O-linked glycosylation; or glycation or glycoconjugation; or glycosyl transfer or glycan transfer; prompt on adding or attaching sugars]
<Adam Silverman, Science - Biology&gt; ~22233~ &lt;Editor: Adam Silverman>

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