Question
Immunotherapy is recommended for tumor cells that have an instability of the “micro-” type of these sequences. For 10 points each:
[10h] Name these regions of short repetitive DNA common in introns or at centromeres. Sequencing services compare the number of tandem repeats of their “micro-” type to predict ancestry.
ANSWER: satellite DNA [or microsatellites or minisatellites; or microsats or satDNA; prompt on junk DNA]
[10e] The shortest microsatellites inside genes are repeats of this many DNA bases—keeping the reading frame intact since it’s also the number of bases in a codon.
ANSWER: 3
[10m] The number of repeats per microsatellite is measured using this lab technique in a capillary. More often, this technique is run in a tank of buffer connected to red and black leads (“leeds”).
ANSWER: agarose gel electrophoresis [or capillary electrophoresis or CE; prompt on running a gel]
<Adam Silverman, Science - Biology> ~23374~ <Editor: Adam Silverman>
Data
Summary
| Tournament | Edition | Exact Match? | Heard | PPB | Easy % | Medium % | Hard % |
|---|---|---|---|---|---|---|---|
| 2024 PACE NSC | 06/08/2024 | Y | 36 | 15.83 | 94% | 64% | 0% |