Question

The prototypical cation–pi (“CAT-ion pie”) interaction in biology binds this molecule to the tryptophan in a ligand-gated ion channel. This compound’s succinyl (“suck-SIH-nil”) derivative, or antagonists (20[1])of its receptors like vecuronium (“veck-yu-ROH-nee-um”), are administered before (20[1])endotracheal intubation as a paralytic. Organophosphate poisoning prevents (20[1])the hydrolysis of an ester bond in this (20[1])quaternary amine. Nightshade toxins like scopolamine (“skuh-PAW-luh-meen”), atropine, (*) muscarine, (10[1])and nicotine (10[2])bind to receptors (10[2])for this compound. (10[5])Receptors (10[1])for this compound are destroyed in myasthenia gravis. Botulinum (10[1])toxin prevents the release (10[1])of this parasympathetic activator into the synaptic cleft. For 10 points, name this neurotransmitter that (10[1])stimulates muscle contraction. ■END■ (10[10])

Back to tossups

Buzzes

Summary