Question

Henrietta Lacks’s doctor George Gey popularized the in vitro use of this protein harvested from rat tails. The letter “O” is unusually common in this protein’s one-letter amino acid sequence. This protein’s type I (“one”) isoform is used to coat cell (20[1])culture plates. Matrigel is a mixture of this (20[1])protein with laminin that mimics a basement membrane (20[1])by adhering (20[2])to (*) integrins. (10[3])G. (10[1])N. Ramachandran proved this protein is a right-handed helix (10[1])of (10[1])three left-handed (10[3])glycine-rich (10[2])helices. (10[3])Cells (10[1])need vitamin (10[1])C to make this (10[1])protein’s (10[2])numerous hydroxy·proline residues. Fibers of this protein guarantee (10[2])the stiffness of the extracellular (10[1])matrix. For 10 points, name this component of connective tissue, (10[1])the most common protein in humans. (10[5])■END■ (10[2])

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